On 19-23 April, The World Federation of Exchanges (the WFE) hosted the 37th edition of its Clearing & Derivatives Conference. This year, the conference took place online. The Conference brought together academics, policy-makers, regulators, CCPs, derivatives markets and practitioners from all around the world to exchange ideas on the opportunities and challenges for the future of central and bilateral clearing in the context of the latest regulatory reforms, market structure changes and technological developments.